Ketamine therapy
Ketamine therapy can help manage central sensitisation pain by “resetting” pain pathways in the nervous system, reducing sensitisation, pain intensity, improving function, and often lowering reliance on harmful opioids.

Chronic pain affects millions of people and often persists long after an injury, illness, or surgery has healed. Understanding its causes and available chronic pain treatment options can help people find appropriate care and improve their quality of life.
Chronic pain is pain that persists for more than three months, often continuing beyond the expected period of healing.
Unlike acute pain—which serves as a warning signal that something is wrong—chronic pain can become a condition in its own right, affecting the nervous system and how the brain processes pain signals. It may arise from an identifiable cause such as injury, surgery, or illness, or occur without a clear underlying source, making an individualised approach to chronic pain treatment important.

Central sensitisation occurs when the brain and spinal cord become overactive, “turning up the volume” on pain signals. This can contribute to central sensitisation pain, where the nervous system becomes increasingly sensitive and amplifies pain signals.
Sensitisation is a key mechanism in chronic pain, where the nervous system becomes hypersensitive and amplifies pain signals, causing ongoing discomfort even after the original injury has healed. This means even light touch, gentle movement, or normal activity can feel intensely painful.
Sensitisation underpins many chronic pain conditions, including fibromyalgia, complex regional pain syndrome (CRPS), and opioid-induced hyperalgesia (OIH). Understanding this mechanism helps explain why standard painkillers often fail and why advanced therapies — such as ketamine — sometimes can be more effective for chronic pain treatment.

Chronic pain is not “just in your head” — it involves real changes in the nervous system that require specialised treatment.
Chronic pain can have wide-ranging effects on a person’s physical, emotional, and social wellbeing. It can disrupt work, relationships, sleep, and mental health, leaving people stuck in a cycle of discomfort and frustration.
Although chronic pain takes many forms, common symptoms and experiences can include

At Anodyne, we provide personalised chronic pain treatment that goes beyond conventional pain medications, including treatment approaches for central sensitisation pain.
Our chronic pain treatment approach helps to reduce pain hypersensitivity and restore function through advanced treatments such as ketamine therapy and stellate ganglion block (SGB) — addressing both the physical and emotional dimensions of chronic pain.
Ketamine therapy can help manage central sensitisation pain by “resetting” pain pathways in the nervous system, reducing sensitisation, pain intensity, improving function, and often lowering reliance on harmful opioids.

Stellate Ganglion Block (SGB) helps calm the overactive sympathetic nervous system, particularly useful in conditions such as CRPS or nerve-related pain. It can also improve blood flow to assist with vascular pain conditions such as Raynaud's.

Chronic pain is complex, often involving physical, psychological, and neurological factors.
At Anodyne, our unique approach to chronic pain treatment brings together psychiatry and pain medicine to address the whole person, not just the symptom.
We understand how isolating and exhausting chronic pain can be. Our team listens, explains your options clearly, and provides care in safe, supportive clinics.
Our chronic pain specialists have experience treating the most complex pain conditions, we offer advanced treatments and practical solutions when other treatments have failed.

Take the next step
If you are struggling with chronic pain and standard treatments haven’t helped, you are not alone. Book an appointment or make an enquiry to explore advanced therapies with Anodyne.