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What is post-polio syndrome?

Post-Polio Syndrome (PPS) is a condition that affects people who have previously had poliomyelitis. It typically develops 15 to 40 years after the initial infection, even in those who had made a good recovery.

For many people who recovered from polio decades ago, the expectation was that the illness had been left behind. PPS can be confusing and frustrating, particularly when symptoms appear long after recovery. Rather than a recurrence of the virus, PPS reflects the long-term effects of the original nerve damage, combined with gradual changes in the nervous system over time.


Understanding Post-polio Syndrome

Why does post-polio syndrome occur?

During the initial polio infection, motor neurons (the nerves that control muscles) are damaged or destroyed. To compensate, the remaining healthy neurons take on additional workload by forming new connections.

Over time, these enlarged motor units become overworked and begin to fail, leading to new symptoms such as weakness and fatigue. This process is gradual but can significantly affect function and quality of life.


Post Polio Syndrome Causes

Common symptoms of post-polio syndrome

Symptoms of PPS vary between individuals and may develop slowly, often being mistaken for normal ageing or unrelated conditions.

Common symptoms may include:

  1. Progressive muscle weakness
  2. Fatigue that is disproportionate to activity
  3. Muscle and joint pain
  4. Reduced endurance and mobility
  5. Difficulty with breathing or swallowing in some cases




Post Polio Syndrome Symptons

How can we help

At Anodyne, we focus on addressing the neurological drivers of persistent pain in PPS, particularly when standard treatments have been insufficient.

PPS is not a single problem but a combination of neurological, muscular, and functional changes, which is why a carefully balanced, individualised approach is essential. Our goal is to improve function while avoiding further strain on the nervous system.

Ketamine therapy

In selected patients, ketamine therapy may help reduce central sensitisation and modulate abnormal pain signalling. This can improve pain control and support better overall function where standard pain management approaches have been insufficient.


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Our unique approach

We combine expertise in pain medicine and advanced interventional techniques to address both the neurological and functional aspects of post-polio syndrome.

PPS affects each person differently, depending on the extent of the original illness and how the body has adapted over time. This requires a clear understanding of the individual's functional limitations, careful balancing of activity and rest and ongoing reassessment as symptoms evolve, ensuring treatment supports long-term stability, not just short-term relief.

Personalised treatment plans built around your symptoms and history

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consultation with a man on a couch in discussion with medical support

Collaboration with your GP, gynaecologist, or specialist to ensure integrated care

2.
A doctor smiling at a patient

Evidence-based use of SGB, supported by growing clinical research

3.
black and white image of nasal spray mist

A focus on rapid symptom relief and restoring daily function

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Why choose anodyne?

We understand how isolating and exhausting it can be when new symptoms emerge long after an illness you thought was behind you.

Our team takes the time to assess your condition thoroughly, explain your options clearly, and provide care in a supportive clinical environment, with treatment that is personalised and focused on maintaining function and quality of life over the long term.

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Want to know more?

Take the next step

If you are experiencing new or worsening symptoms after previous polio, exploring the underlying cause is an important first step. Book an appointment or make an enquiry to learn more about personalised treatment options for post-polio syndrome.

Frequently Asked Questions